Evolving paradigm in thrombophilia screening
نویسندگان
چکیده
منابع مشابه
Thrombophilia Screening.
Although controversial, screening for thrombophilia has become common. Testing for antiphospholipid antibodies is indicated in order to guide treatment decisions if there is clinical suspicion for antiphospholipid syndrome. The utility of identifying other thrombophilias in symptomatic venous thromboembolism (VTE) is questionable, as the risk of recurrence does not appear to be increased by an ...
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In this issue of Blood, Holzhauer et al have determined a novel method of identifying patients with protein C, protein S, and antithrombin deficiency who are at increased risk of developing venous thromboembolism (VTE; see figure). Children with VTE and their relatives were screened for inherited thrombophilia including proteins C and S and antithrombin deficiency; and Factor (F)V G1691A and FI...
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1 Division of Developmental Medicine, University of Glasgow, UK 2 Scottish Intercollegiate Guidelines Network, Edinburgh, UK 3 Division of Cardiovascular and Medical Sciences, University of Glasgow, UK 4 Ninewells Hospital, Dundee, UK 5 Department of Medicine and Therapeutics, University of Aberdeen, UK 6 Fife Acute Hospital Trust, Fife, UK 7 Department of Obstetrics and Gynaecology, Imperial C...
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متن کاملThrombophilia screening: a matter of debate.
In the last ten years, several risk factors that increase the risk of venous thrombosis have been discovered. Venous thrombosis is a multicausal disease in which several risk factors, both genetic and acquired, have to occur simultaneously to cause thrombosis. This means that most individuals with single thrombophilia are asymptomatic. Although testing thrombosis patients and their relatives fo...
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ژورنال
عنوان ژورنال: Blood Coagulation & Fibrinolysis
سال: 2019
ISSN: 0957-5235
DOI: 10.1097/mbc.0000000000000809